The TSH receptor (TSHR) comprises an extracellular leucine-rich domain (LRD) linked by a hinge region to the transmembrane domain (TMD).Insight into the orientation of these components to each other is required for understanding how ligands activate the receptor.We previously identified residue E251 at the LRD-hinge junction as contributing to coup
Since 1985 a resident community of Atlantic spotted dolphins (Stenella frontalis), and bottlenose dolphins (Tursiops truncatus), have been studied underwater in the Bahamas.Over 200 individuals of both species have been identified and observed over the years.Basic correlations with sound patterns and behavior such as whistles during contact/reunion
BackgroundFever in neutropenia (FN) is a potentially life-threatening complication of chemotherapy in pediatric cancer patients.The current standard of care at most institutions is emergency hospitalization and empirical initiation of broad-spectrum antibiotic therapy.MethodsWe analyzed in retrospect FN episodes with bacteremia in pediatric cancer
Zoonotic-origin infectious diseases are one of the major concerns of human and veterinary health systems.Ticks, as vectors of several zoonotic diseases, are ranked second only to mosquitoes as vectors.Many ticks’ transmitted infections are Cutlery Basket still endemic in the Americas, Europe, and Africa and represent approximately 17% of their in